Sulfuric Acid → HCID 57159555, compound

HRID 2120455Notes

Reaction equation

HRID 2120455 reaction equation
S(=O)(=O)(O)O.C(OC[O:10][C:11]1[CH:12]=[C:13]([CH:22]=[CH:23][C:24]2[CH:25]=[C:26]([CH:30]=[CH:31][CH2:32][CH2:33][CH2:34][C:35]([CH3:38])([OH:37])[CH3:36])[CH:27]=[CH:28][CH:29]=2)[CH:14]=[C:15]([O:17]COCC)[CH:16]=1)C>CO.C1COCC1>[OH:37][C:35]([CH3:38])([CH3:36])[CH2:34][CH2:33][CH2:32][CH:31]=[CH:30][C:26]1[CH:25]=[C:24]([CH:23]=[CH:22][C:13]2[CH:12]=[C:11]([OH:10])[CH:16]=[C:15]([OH:17])[CH:14]=2)[CH:29]=[CH:28][CH:27]=1

Participants

5

Reactant 2

HCID 1118Sulfuric AcidHCID 69685823HCID 69685823, compound

Product 1

HCID 57159555HCID 57159555, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolvent2×HCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to Example 1(j), by reacting 0.15 ml of concentrated sulphuric acid in 3 ml of methanol with 314 mg (0.67 mmol) of 7-{3-[2-(3,5-bis-ethoxymethoxyphenyl)vinyl]phenyl}-2-methylhept-6-en-2-ol in 3 ml of methanol and 3 ml of THF, after purification on a silica column (ethyl acetate 50-heptane 50), white crystals (m=206 mg; Y=91%) are obtained. m.p.=60-4° C.

Workup

  1. customafter purification on a silica column (ethyl acetate 50-heptane 50), white crystals (m=206 mg; Y=91%)
  2. customare obtained

Sources & evidence

ORD record
ord-bbe5b7e7c2a8495d956646cc780f9822
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

Loading…