Sulfuric Acid → HCID 67278787, compound

HRID 2120456Notes

Reaction equation

HRID 2120456 reaction equation
S(=O)(=O)(O)O.C(OC[O:10][C:11]1[CH:12]=[C:13]([CH:22]=[CH:23][C:24]2[CH:25]=[C:26]([CH:30]=[CH:31][CH2:32][CH2:33][CH2:34][CH2:35][C:36]([CH2:40][CH3:41])([OH:39])[CH2:37][CH3:38])[CH:27]=[CH:28][CH:29]=2)[CH:14]=[C:15]([O:17]COCC)[CH:16]=1)C>CO.C1COCC1>[CH2:37]([C:36]([OH:39])([CH2:40][CH3:41])[CH2:35][CH2:34][CH2:33][CH2:32][CH:31]=[CH:30][C:26]1[CH:25]=[C:24]([CH:23]=[CH:22][C:13]2[CH:14]=[C:15]([OH:17])[CH:16]=[C:11]([OH:10])[CH:12]=2)[CH:29]=[CH:28][CH:27]=1)[CH3:38]

Participants

5

Reactant 2

HCID 1118Sulfuric AcidHCID 69685921HCID 69685921, compound

Product 1

HCID 67278787HCID 67278787, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolvent2×HCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to Example 1(j), by reacting 0.3 ml of concentrated sulphuric acid in 7 ml of methanol with 700 mg (1.41 mmol) of 9-{3-[2-(3,5-bis-ethoxymethoxyphenyl)vinyl]phenyl}-3-ethylnon-8-en-3-ol in 7 ml of methanol and 7 ml of THF, after purification on a silica column (ethyl acetate 40-heptane 60), beige crystals (m=477 mg; Y=77%) are obtained. m.p.=98-102° C.

Workup

  1. customafter purification on a silica column (ethyl acetate 40-heptane 60), beige crystals (m=477 mg; Y=77%)
  2. customare obtained

Sources & evidence

ORD record
ord-95003c4c7cd24febac7d2fd7b6b67dd5
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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