Methanol → HCID 57100366, compound

Participants

Reaction Steps

In a manner similar to Example 1(j), by reacting 0.2 ml of concentrated sulphuric acid in 3 ml of methanol with 350 mg (0.6 mmol) of 2-{3-[2-(3,5-bis-ethoxymethoxyphenyl)vinyl]phenyl}-8-methyl-8-(tetrahydropyran-2-yloxy)nonan-2-ol in 3 ml of methanol and 3 ml of THF, after purification on a silica column (ethyl acetate 60-heptane 40), white crystals (m=76 mg; Y=32%) are obtained. m.p.=65-75° C.

Provenance & Evidence