Sulfuric Acid → HCID 57121444, compound

HRID 2120462Notes

Reaction equation

HRID 2120462 reaction equation
S(=O)(=O)(O)O.C(OC[O:10][C:11]1[CH:12]=[C:13]([CH:22]=[CH:23][C:24]2[CH:25]=[C:26]([CH:30]=[CH:31][CH2:32][CH2:33][CH2:34][CH:35]([OH:39])[CH:36]([CH3:38])[CH3:37])[CH:27]=[CH:28][CH:29]=2)[CH:14]=[C:15]([O:17]COCC)[CH:16]=1)C>CO.C1COCC1>[OH:39][CH:35]([CH:36]([CH3:38])[CH3:37])[CH2:34][CH2:33][CH2:32][CH:31]=[CH:30][C:26]1[CH:25]=[C:24]([CH:23]=[CH:22][C:13]2[CH:12]=[C:11]([OH:10])[CH:16]=[C:15]([OH:17])[CH:14]=2)[CH:29]=[CH:28][CH:27]=1

Participants

5

Reactant 2

HCID 1118Sulfuric AcidHCID 69685704HCID 69685704, compound

Product 1

HCID 57121444HCID 57121444, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to Example 1(j), by reacting 0.3 ml of concentrated sulphuric acid in 2.5 ml of methanol with 126 mg (0.27 mmol) of 8-{3-[2-(3,5-bis-ethoxymethoxyphenyl)vinyl]phenyl}-2-methyloct-7-en-3-ol in 2.5 ml of THF, after purification on a silica column (ethyl acetate 40-heptane 60), a beige powder (m=60 mg; Y=63%) is obtained.

Workup

  1. customafter purification on a silica column (ethyl acetate 40-heptane 60)
  2. customa beige powder (m=60 mg; Y=63%) is obtained

Sources & evidence

ORD record
ord-51ab2332811f46e4ba6f7c93c0365d43
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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