Sulfuric Acid → HCID 57240943, compound

HRID 2120464Notes

Reaction equation

HRID 2120464 reaction equation
S(=O)(=O)(O)O.O[C:7]([C:17]1[CH:18]=[C:19]([CH:23]=[CH:24][C:25]2[CH:26]=[C:27]([OH:32])[CH:28]=[C:29]([OH:31])[CH:30]=2)[CH:20]=[CH:21][CH:22]=1)([CH3:16])[CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:15])([CH3:14])[CH3:13]>C1COCC1>[OH:15][C:12]([CH3:14])([CH3:13])[CH2:11][CH2:10][CH2:9][CH:8]=[C:7]([C:17]1[CH:18]=[C:19]([CH:23]=[CH:24][C:25]2[CH:30]=[C:29]([OH:31])[CH:28]=[C:27]([OH:32])[CH:26]=2)[CH:20]=[CH:21][CH:22]=1)[CH3:16]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 67278647HCID 67278647, compound

Product 1

HCID 57240943HCID 57240943, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

In a manner similar to Example 1(j), by reacting 0.09 ml of concentrated sulphuric acid in 3 ml of THF with 152 mg (0.41 mmol) of 5-{2-[3-(1,6-dihydroxy-1,6-dimethylheptyl)phenyl]vinyl}benzene-1,3-diol in 1.5 ml of THF, after purification on a silica column (ethyl acetate 50-heptane 50), a yellow powder (m=65 mg; Y=45%) is obtained. m.p.=55-60° C.

Workup

  1. customafter purification on a silica column (ethyl acetate 50-heptane 50)
  2. customa yellow powder (m=65 mg; Y=45%) is obtained

Sources & evidence

ORD record
ord-f362127d53434130bbfc8730656d8029
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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