Lithium borohydride → HCID 69685513, compound

HRID 2120480Notes

Reaction equation

HRID 2120480 reaction equation
[OH:1][C:2]([CH3:33])([CH3:32])[CH2:3][CH2:4][CH2:5][CH2:6]/[CH:7]=[C:8](/[C:10]1[CH:11]=[C:12]([CH:29]=[CH:30][CH:31]=1)[O:13][CH2:14][C:15]1[CH:16]=[C:17]([C:25](OC)=[O:26])[C:18](=[CH:23][CH:24]=1)[C:19](OC)=[O:20])\[CH3:9].[BH4-].[Li+]>>[OH:26][CH2:25][C:17]1[CH:16]=[C:15]([CH:24]=[CH:23][C:18]=1[CH2:19][OH:20])[CH2:14][O:13][C:12]1[CH:11]=[C:10](/[C:8](/[CH3:9])=[CH:7]/[CH2:6][CH2:5][CH2:4][CH2:3][C:2]([CH3:32])([OH:1])[CH3:33])[CH:31]=[CH:30][CH:29]=1

Participants

3

Reactant 2

HCID 4148881Lithium borohydrideHCID 69928039HCID 69928039, compound

Product 1

HCID 69685513HCID 69685513, compound

Procedure

In a manner similar to Example 53(e), by reacting 204 mg (0.46 mmol) of dimethyl 4-[3-((E)-7-hydroxy-1,7-dimethyloct-1-enyl)phenoxymethyl]-phthalate (prepared in a manner similar to Examples 72(a-c)) with 30 mg (1.4 mmol) of lithium borohydride, a colourless oil is obtained (m=146 mg; Y=82%).

Workup

  1. customa colourless oil is obtained (m=146 mg; Y=82%)

Sources & evidence

ORD record
ord-b8816c33e4da40b9a0523778177825f8
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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