Lithium borohydride → HCID 86759343, compound

HRID 2120487Notes

Reaction equation

HRID 2120487 reaction equation
[OH:1][C:2]([CH3:33])([CH3:32])/[CH:3]=[CH:4]/[CH:5]=[CH:6]/[C:7]([C:10]1[CH:11]=[C:12]([CH:29]=[CH:30][CH:31]=1)[O:13][CH2:14][C:15]1[CH:16]=[C:17]([C:25](OC)=[O:26])[C:18](=[CH:23][CH:24]=1)[C:19](OC)=[O:20])([CH3:9])[CH3:8].[BH4-].[Li+]>>[OH:26][CH2:25][C:17]1[CH:16]=[C:15]([CH:24]=[CH:23][C:18]=1[CH2:19][OH:20])[CH2:14][O:13][C:12]1[CH:11]=[C:10]([C:7]([CH3:8])([CH3:9])/[CH:6]=[CH:5]/[CH:4]=[CH:3]/[C:2]([CH3:33])([OH:1])[CH3:32])[CH:31]=[CH:30][CH:29]=1

Participants

3

Reactant 2

HCID 4148881Lithium borohydrideHCID 23439843HCID 23439843, compound

Product 1

HCID 86759343HCID 86759343, compound

Procedure

In a manner similar to Example 53(e), by reacting 360 mg (0.8 mmol) of dimethyl 4-[3-((2E,4E)-6-hydroxy-1,1,6-trimethylhepta-2,4-dienyl)phenoxymethyl]phthalate (prepared from the previous product in a manner similar to Example 64(d)) with 70 mg (3.2 mmol) of lithium borohydride, a colourless oil is obtained (m=220 mg; Y=70%).

Workup

  1. customa colourless oil is obtained (m=220 mg; Y=70%)

Sources & evidence

ORD record
ord-63bdbc337e31479e81c40409865ba968
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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