Dimethylamine → HCID 86586428, compound

HRID 2120565Notes

Reaction equation

HRID 2120565 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7]C#N)[CH:2]=1.C(OC([N:19]([CH3:21])[CH3:20])N(C)C)(C)(C)C.C[NH:23][CH3:24].[C:25](O)(C)(C)C>>[CH3:21][N:19]([CH:7]=[C:3]1[CH:4]=[CH:5][CH:6]=[N:1][CH:2]1[CH2:25][C:24]#[N:23])[CH3:20]

Participants

5

Reactant 4

HCID 674DimethylamineHCID 6386tert-ButanolHCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 809233-Pyridineacetonitrile

Product 1

HCID 86586428HCID 86586428, compound

Procedure

3.00 g (25.4 mmol) of 3-pyridylacetonitrile and 4.23 g (25.4 mmol) tert-butoxybis(dimethylamino)methane were stirred at 100° C. for 2 h. In the course of this, liberated dimethylamine and t-butanol were led off to the atmosphere by a slight reduced pressure flow by means of a vacuum pump. After cooling, the deposited solid was filtered, washed with a little H2O and the title compound was thus obtained.

Workup

  1. temperatureAfter cooling
  2. filtrationthe deposited solid was filtered
  3. washwashed with a little H2O

Sources & evidence

ORD record
ord-757791d466b545f1a378b491ebf9d0c3
Source dataset
uspto-grants-2004_02
Patent number
US06693102B2

Reaction notes

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