Methanol → 2-[4-(2,2-dimethylbutyl)-1-trityl-1H-imidazol-2-yl]-1-[4-(5-fluoropyridin-2-yl)phenyl]ethanol
Reaction equation
[BH4-:1].[CH3:3][C:4]([CH2:5][c:6]1[n:7][c:8]([CH2:30][C:31](=[O:32])[c:33]2[cH:34][cH:35][c:36](-[c:39]3[n:40][cH:41][c:42]([F:45])[cH:43][cH:44]3)[cH:37][cH:38]2)[n:9]([C:11]([c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:10]1)([CH2:46][CH3:47])[CH3:48].[CH3:49][OH:50].[Li+:2]>>[CH3:3][C:4]([CH2:5][c:6]1[n:7][c:8]([CH2:30][CH:31]([OH:32])[c:33]2[cH:34][cH:35][c:36](-[c:39]3[n:40][cH:41][c:42]([F:45])[cH:43][cH:44]3)[cH:37][cH:38]2)[n:9]([C:11]([c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:10]1)([CH2:46][CH3:47])[CH3:48]Participants
5
Sources & evidence
- ORD record
- ord-8890c56eeb9b4644bb1a01283cc09fa4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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