HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2120571Generated: October 30, 2026
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide → HCID 178517574, compound
https://huagongshe.com/reaction/2120571
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide | HCID 11403986 | — |
| Reactant | HCID 12661050 | HCID 12661050 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 178517574 | HCID 178517574 | — |
Reaction Steps
3.27 g (12.1 mmol)1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximid-amide from example III were suspended in 40 ml toluene, reacted with 2.88 g (12.1 mmol) diethyl 2-(4-pyridinyl)malonate (commercially available by Mercachem) and stirred overnight at 140° C. For purification the deposited solid is sucked off and dried under high vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06693102B2 |
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| Source dataset | uspto-grants-2004_02 |
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| ORD ID | ord-67ad2f981dfa4174ba73ef7bd30ace67 |
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| Source note | uspto-grants-2004_02 |
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