Phosphoric Acid → HCID 86591062, compound

HRID 2120928Notes

Reaction equation

[C:1]([OH:14])(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].P(=O)(O)(O)[OH:16].[CH2:20]1[O:22][CH:21]1[CH2:23][OH:24].[O].[O:26]1CC1>C(O)C(O)CO>[C:1]([OH:14])(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[OH:22][CH2:20][CH:21]([CH2:23][OH:24])[OH:26].[OH:22][CH2:20][CH:21]([CH2:23][OH:24])[OH:16].[OH:22][CH2:20][CH:21]([CH2:23][OH:24])[OH:13].[OH:22][CH2:20][CH:21]([CH2:23][OH:24])[OH:13].[OH:22][CH2:20][CH:21]([CH2:23][OH:24])[OH:13].[OH:22][CH2:20][CH:21]([CH2:23][OH:24])[OH:13]

Participants

Conditions

Temperature: 140 °C

Procedure

A four-necked flask equipped with a tube for supplying nitrogen gas, a stirrer, a cooler, a thermostat, and a dropwise funnel was charged with 100.16 parts by weight of lauric acid and 0.0622 part by weight of phosphoric acid (a purity of 85%) followed by heating to 140° C. Subsequently, 222.24 parts by weight (molar ratio of glycidol/lauric acid=6) of glycidol was added drowpwise over 5 hours to allow to react until oxirane oxygen concentration in the reactant attains below 0.1% while maintaining the reaction temperature at 140° C. for 26 hours, to obtain approximately 300 parts by weight of a fatty acid esters composition of a polyglycerine (a hexaglycerine monolaurate composition). Content of the monoester was 87.7% based on the HPLC analytical condition No. 1 as described hereinabove.

Workup

customA four-necked flask equipped with a tube
temperaturewhile maintaining the reaction temperature at 140° C. for 26 hours

Sources & evidence

ORD record: ord-58734c948fde4009a80352e2e2d20cb3
Source dataset: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06693150B1

Reaction notes

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