Sodium Methoxide → HCID 69892025, compound

Participants

Reaction Steps

N-[4-(2-(4-chloropyridin-3-yl)ethenyl)-2-(2-methylphenyl)benzoyl]methionine methyl ester, prepared as in Example 1040, (62 mg, 0.12 mmol) was dissolved in DMF (1 mL) and treated with NaOMe (0.5 M in MeOH, 1.25 mL, 0.63 mmol). After stirring 18 hours at ambient temperature, the reaction was evaporated and lyophilized from water to provide 68 mg of the title compound. MS m/e 477 (M+H)+.

Provenance & Evidence