HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 10126062, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 69997187 | HCID 69997187 | — |
| Product | HCID 10126062 | HCID 10126062 | — |
Reaction Steps
0.4 g of (8R, 9R)-8-hydroxy-6-methoxymethyl-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydroimidazo[1,2-h]-[1,7]naphthyridin-7-one are reacted with sodium borohydride analogously to Example 15. After purification on silica gel (mobile phase: methylene chloride/methanol=100/3), 120 mg of the title compound [Rf=0.44 (methylene chloride/methanol=13/1)] of melting point 202-5° C. (decomp.) are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06696461B2 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-2819f4f6698949d7ae119dc102af536f |
| Source note | uspto-grants-2004_02 |