N-Methylethylamine → N'-(4-{[3-(1,1-dimethylethyl)phenyl]oxy}-2,5-dimethylphenyl)-N-ethyl-N-methylthiourea

Participants

Reaction Steps

Ethylmethylamine (450 mg) is added dropwise to a solution of 1-{[3-(1,1-dimethylethyl)phenyl]oxy}-4-isothiocyanato-2,5-dimethylbenzene (1.9 g) in tetrahydrofuran (6 ml) at 0° C. The reaction mixture obtained is stirred at room temperature for 1 h and then concentrated and triturated with heptane. The title product is obtained in the form of a white precipitate.

Provenance & Evidence