HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-((S)-2-Azidopropyl)-1,7,8,9-tetrahydro-pyrano[2,3-g]indazol-8-ol → 1-((S)-2-Aminopropyl)-1,7,8,9-tetrahydro-pyrano[2,3-g]indazol-8-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-((S)-2-Azidopropyl)-1,7,8,9-tetrahydro-pyrano[2,3-g]indazol-8-ol | HCID 86759652 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-((S)-2-Aminopropyl)-1,7,8,9-tetrahydro-pyrano[2,3-g]indazol-8-ol | HCID 9834763 | 88% |
Reaction Steps
A solution of the product from Step A in methanol was treated as described in Example 2, Step J to give the free base as an amorphous solid (0.36 g, 88%): mp 46-51° C.; GCMS(Cl+) m/z 248 (M+H). Analysis. Calculated for C13H17N3O2.0.1H2O: C, 62.68; H, 6.96; N, 16.97. Found: C, 62.55; H, 7.03; N, 16.64.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06696476B2 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-ac3ac85eed0d448594f6b393a655c64d |
| Source note | uspto-grants-2004_02 |