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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2121941Generated: November 1, 2026

Ethylamine → N-Ethyl-3-nitropyridin-4-amine

https://huagongshe.com/reaction/2121941

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
Reactant4-Chloro-3-nitropyridineHCID 2735781—
ProductN-Ethyl-3-nitropyridin-4-amineHCID 21937597—

Reaction Steps

In a manner similar to example 31, the title compound was prepared from 4-chloro-3-nitropyridine, prepared according to published procedure [J. Med. Chem. 1996, 39, 487-493], and ethylamine. 1H-NMR (CDCl3): δ 9.22 (1H, s), 8.30 (1H, d), 8.10 (1H, br s), 6.71 (1H, d), 3.40 (2H, m), 1.39 (3H, t).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06696473B2
Source datasetuspto-grants-2004_02
ORD IDord-4dd46c2879854acb83494dab66875f27
Source noteuspto-grants-2004_02