Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 441116 | HCID 441116 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 23434938 | HCID 23434938 | 78.4% |
Reaction Steps
35.5 g (0.298 mol) of thionyl chloride were added dropwise at 0° C. to the solution of 50 g (0.199 mol) of the acid of Example 4 in 200 ml of diethyl ether and 23.6 g (0.298 mol) of pyridine. The solution was stirred for 6 hours at 20 to 25° C. and then filtered. After the solvent had been distilled off, 42.1 g of the product were obtained, and this was reacted further without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06696607B2 |
|---|
| Source dataset | uspto-grants-2004_02 |
|---|
| ORD ID | ord-75e7ea7a7009443db6c122859115e526 |
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| Source note | uspto-grants-2004_02 |
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