1-Methylpiperazine → 5-({1-[2-Chloro-4-(1-hydroxy-1-methylethyl)benzyl]-1H-indazol-5-yl}methylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one

HRID 2122523Notes

Reaction equation

HRID 2122523 reaction equation
[CH3:32][N:33]1[CH2:34][CH2:35][NH:36][CH2:37][CH2:38]1.[Cl:1][c:2]1[c:3]([CH2:4][n:5]2[n:6][cH:7][c:8]3[cH:9][c:10]([CH:14]=[C:15]4[C:16](=[O:23])[N:17]=[C:18]([S:20][CH2:21][CH3:22])[S:19]4)[cH:11][cH:12][c:13]23)[cH:24][cH:25][c:26]([C:28]([CH3:29])([CH3:30])[OH:31])[cH:27]1>>[Cl:1][c:2]1[c:3]([CH2:4][n:5]2[n:6][cH:7][c:8]3[cH:9][c:10]([CH:14]=[C:15]4[C:16](=[O:23])[N:17]=[C:18]([N:36]5[CH2:35][CH2:34][N:33]([CH3:32])[CH2:38][CH2:37]5)[S:19]4)[cH:11][cH:12][c:13]23)[cH:24][cH:25][c:26]([C:28]([CH3:29])([CH3:30])[OH:31])[cH:27]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 672417045-{1-[2-Chloro-4-(1-hydroxy-1-methyl-ethyl)benzyl]-1H-indazol-5-ylmethylene}-2-ethylsulfanyl-thiazol-4-one

Product 1

HCID 672434255-({1-[2-Chloro-4-(1-hydroxy-1-methylethyl)benzyl]-1H-indazol-5-yl}methylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one

Sources & evidence

ORD record
ord-7be9638c9f3744a39e5be8f620944572
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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