Hydrochloric Acid → Furo[3,2-c]pyridin-6-amine, 7-[1-(2,6-dichloro-3,5-difluorophenyl)ethoxy]-3-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-

HRID 2122621Notes

Reaction equation

HRID 2122621 reaction equation
[CH2:43]1[O:44][CH2:45][CH2:46][O:47][CH2:48]1.[ClH:42].[NH2:1][c:2]1[c:3]([O:29][CH:30]([CH3:31])[c:32]2[c:33]([Cl:41])[c:34]([F:40])[cH:35][c:36]([F:39])[c:37]2[Cl:38])[c:4]2[c:5]([cH:6][n:7]1)[c:8](-[c:11]1[cH:12][n:13][n:14]([CH:16]3[CH2:17][CH2:18][N:19]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:20][CH2:21]3)[cH:15]1)[cH:9][o:10]2>>[NH2:1][c:2]1[c:3]([O:29][CH:30]([CH3:31])[c:32]2[c:33]([Cl:41])[c:34]([F:40])[cH:35][c:36]([F:39])[c:37]2[Cl:38])[c:4]2[c:5]([cH:6][n:7]1)[c:8](-[c:11]1[cH:12][n:13][n:14]([CH:16]3[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[cH:15]1)[cH:9][o:10]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 57812454HCID 57812454, compound

Product 1

HCID 57812347Furo[3,2-c]pyridin-6-amine, 7-[1-(2,6-dichloro-3,5-difluorophenyl)ethoxy]-3-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-

Sources & evidence

ORD record
ord-203a6cff62df473ab1b3c87e2cb0f5ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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