Hydrochloric Acid → 1-[(3-Fluorophenyl)methyl]-4-(piperazin-1-yl)-1,3-dihydro-2H-indol-2-one

HRID 2123233Notes

Reaction equation

HRID 2123233 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]3[c:19]([cH:20][cH:21][cH:22]2)[N:18]([CH2:23][c:24]2[cH:25][c:26]([F:30])[cH:27][cH:28][cH:29]2)[C:17](=[O:31])[CH2:16]3)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:33][CH2:34][OH:35].[CH3:36][CH2:37][O:38][CH2:39][CH3:40].[CH3:41][CH2:42][OH:43].[ClH:32]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]3[c:19]([cH:20][cH:21][cH:22]2)[N:18]([CH2:23][c:24]2[cH:25][c:26]([F:30])[cH:27][cH:28][cH:29]2)[C:17](=[O:31])[CH2:16]3)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 702Ethanol2×HCID 3283Diethyl EtherHCID 57834987HCID 57834987, compound

Product 1

HCID 160422241-[(3-Fluorophenyl)methyl]-4-(piperazin-1-yl)-1,3-dihydro-2H-indol-2-one

Sources & evidence

ORD record
ord-72ca50608ca6466e9f25d681c91eb0f6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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