Pyridine → Tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate

HRID 2123352Notes

Reaction equation

HRID 2123352 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[CH2:32]([Cl:33])[Cl:34].[Cl:20][C:21]([Cl:22])([O:23][C:24](=[O:25])[O:26][C:27]([Cl:28])([Cl:29])[Cl:30])[Cl:31].[cH:14]1[cH:15][cH:16][n:17][cH:18][cH:19]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([C:21]([Cl:20])=[O:23])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 94429TriphosgeneHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 11334154Tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-0e4e745c9cd64c9799953a12715381e4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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