Water → 4-Benzyloxycarbonyl-1-(4-fluorobenzyl)-3,4-dihydropyrazin-2(1H)-one

HRID 2123549Notes

Reaction equation

HRID 2123549 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH2:12][C:13](=[O:14])[N:15]([CH2:16][c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1)[CH2:24][CH:25]([O:26][CH3:27])[O:28][CH3:29].[CH3:42][c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1.[OH2:30].[c:31]1([CH3:32])[cH:33][cH:34][c:35]([S:36]([OH:37])(=[O:38])=[O:39])[cH:40][cH:41]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][C:13](=[O:14])[N:15]([CH2:16][c:17]2[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]2)[CH:24]=[CH:25]1

Participants

5

Reactant 4

HCID 962WaterHCID 1140TolueneHCID 6101p-Toluenesulfonic acidHCID 59813049N2-Benzyloxycarbonyl-N1-(2,2-dimethoxyethyl)-N1-(4-fluorobenzyl)-glycinamide

Product 1

HCID 598130504-Benzyloxycarbonyl-1-(4-fluorobenzyl)-3,4-dihydropyrazin-2(1H)-one

Sources & evidence

ORD record
ord-853f74196a394ad89d9372522dbb7f81
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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