Lithium ion → N-(2-Amino-3-fluorobenzyl)-1-benzylpiperidin-4-amine
Reaction equation
[Al+3:2].[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[NH2:7][c:8]1[c:9]([C:10](=[O:11])[NH:12][CH:13]2[CH2:14][CH2:15][N:16]([CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[CH2:17][CH2:18]2)[cH:26][cH:27][cH:28][c:29]1[F:30].[O:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1>>[NH2:7][c:8]1[c:9]([CH2:10][NH:12][CH:13]2[CH2:14][CH2:15][N:16]([CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[CH2:17][CH2:18]2)[cH:26][cH:27][cH:28][c:29]1[F:30]Participants
6
Sources & evidence
- ORD record
- ord-b3e69f3a89c247018e6ec6a343e83b64
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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