Dichloromethane → Ethyl 5-cyclobutyl-3-(hydroxymethyl)-4-isoxazolecarboxylate

HRID 212399Notes

Reaction equation

HRID 212399 reaction equation
[CH:1]1([c:5]2[c:6]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[c:7]([CH2:10][O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[n:8][o:9]2)[CH2:2][CH2:3][CH2:4]1.[Cl:28][CH2:29][Cl:30].[OH:21][C:22]([C:23]([F:24])([F:25])[F:26])=[O:27]>>[CH:1]1([c:5]2[c:6]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[c:7]([CH2:10][OH:11])[n:8][o:9]2)[CH2:2][CH2:3][CH2:4]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 59321584Ethyl 5-cyclobutyl-3-{[(1,1-dimethylethyl)oxy]methyl}-4-isoxazolecarboxylate

Product 1

HCID 59321537Ethyl 5-cyclobutyl-3-(hydroxymethyl)-4-isoxazolecarboxylate

Sources & evidence

ORD record
ord-3d790f98875c44dc862a3fa0a2e43508
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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