Methanol → 2-chloro-7-(2,4-difluorophenyl)-N-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine

HRID 2124227Notes

Reaction equation

HRID 2124227 reaction equation
[CH3:20][NH2:21].[CH3:22][OH:23].[Cl:1][c:2]1[n:3][c:4]([Cl:19])[c:5]2[c:6]([n:7]1)[CH:8]([c:11]1[c:12]([F:18])[cH:13][c:14]([F:17])[cH:15][cH:16]1)[CH2:9][CH2:10]2>>[Cl:1][c:2]1[n:3][c:4]([NH:21][CH3:20])[c:5]2[c:6]([n:7]1)[CH:8]([c:11]1[c:12]([F:18])[cH:13][c:14]([F:17])[cH:15][cH:16]1)[CH2:9][CH2:10]2

Participants

4

Reactant 3

HCID 887MethanolHCID 6329MethylamineHCID 580755852,4-Dichloro-7-(2,4-difluorophenyl)-6,7-dihydro-5H-cyclopenta[D]pyrimidine

Product 1

HCID 580757472-chloro-7-(2,4-difluorophenyl)-N-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-158bbba45ece46a08749c79b668b0bed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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