Dimethylformamide → Ethyl 4-(hydroxymethyl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylate
Reaction equation
[Ag+:35].[Br:1][CH2:2][c:3]1[n:4][c:5](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[s:6][c:7]1[C:8](=[O:9])[O:10][CH2:11][CH3:12].[F:28][C:29]([F:30])([F:31])[C:32]([O-:33])=[O:34].[O:23]=[CH:24][N:25]([CH3:26])[CH3:27]>>[CH2:2]([c:3]1[n:4][c:5](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[s:6][c:7]1[C:8](=[O:9])[O:10][CH2:11][CH3:12])[OH:23]Participants
5
Sources & evidence
- ORD record
- ord-2b0ae2afd756409eaa456e5aa0b5d37e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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