Methanol → 3-(3-Amino-isoxazol-5-yl)-6-chloro-4-phenyl-1H-quinolin-2-one
Reaction equation
[C:1]([NH:2][c:3]1[cH:4][c:5]([CH2:6][C:7]([OH:8])=[O:9])[o:10][n:11]1)([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[CH3:83][OH:84].[Cl:30][c:31]1[cH:32][c:33]2[c:34](-[c:67]3[cH:68][cH:69][cH:70][cH:71][cH:72]3)[c:35](-[c:42]3[cH:43][c:44]([NH:47][C:48]([c:49]4[cH:50][cH:51][cH:52][cH:53][cH:54]4)([c:55]4[cH:56][cH:57][cH:58][cH:59][cH:60]4)[c:61]4[cH:62][cH:63][cH:64][cH:65][cH:66]4)[n:45][o:46]3)[c:36](=[O:41])[nH:37][c:38]2[cH:39][cH:40]1.[Cl:73][CH2:74][Cl:75].[F:76][C:77]([F:78])([F:79])[C:80]([OH:81])=[O:82]>>[Cl:30][c:31]1[cH:32][c:33]2[c:34](-[c:67]3[cH:68][cH:69][cH:70][cH:71][cH:72]3)[c:35](-[c:42]3[cH:43][c:44]([NH2:47])[n:45][o:46]3)[c:36](=[O:41])[nH:37][c:38]2[cH:39][cH:40]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-2915d0abbc3446ae80b5ebc2eb40124a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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