Dimethylacetamide → Tert-butyl 4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazine-1-carboxylate

HRID 2124335Notes

Reaction equation

HRID 2124335 reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[N:19]1[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]1.[CH3:25][C:26]([N:27]([CH3:28])[CH3:29])=[O:30].[Cl:1][c:2]1[cH:3][n:4][c:5]([C:8]([F:9])([F:10])[F:11])[n:6][cH:7]1>>[c:2]1([N:22]2[CH2:21][CH2:20][N:19]([C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[CH2:24][CH2:23]2)[cH:3][n:4][c:5]([C:8]([F:9])([F:10])[F:11])[n:6][cH:7]1

Participants

4

Reactant 3

HCID 31374DimethylacetamideHCID 143452tert-Butyl piperazine-1-carboxylateHCID 336979605-Chloro-2-(trifluoromethyl)pyrimidine

Product 1

HCID 53485514Tert-butyl 4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazine-1-carboxylate

Sources & evidence

ORD record
ord-a4a5eb82d29e4aceb635419f3ea4ae00
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…