Hydrochloric Acid → 1,3-Diacetoxy-2-(2,4-difluorophenyl)-2-propanol

HRID 2124469Notes

Reaction equation

HRID 2124469 reaction equation
[C:15]([CH3:16])(=[O:17])[O:18][CH2:19][C:20](=[O:21])[CH2:22][O:23][C:24]([CH3:25])=[O:26].[CH2:10]([Li:11])[CH2:12][CH2:13][CH3:14].[CH3:28][CH2:29][O:30][CH2:31][CH3:32].[CH3:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38].[ClH:27].[F:1][c:2]1[c:3]([Br:9])[cH:4][cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[c:3]([C:20]([CH2:19][O:18][C:15]([CH3:16])=[O:17])([OH:21])[CH2:22][O:23][C:24]([CH3:25])=[O:26])[cH:4][cH:5][c:6]([F:8])[cH:7]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 8058HexaneHCID 676741-Bromo-2,4-difluorobenzeneHCID 2434181,3-DiacetoxyacetoneHCID 178418339Butyllithium

Product 1

HCID 154634621,3-Diacetoxy-2-(2,4-difluorophenyl)-2-propanol

Sources & evidence

ORD record
ord-934d8135df574179b2800589544b4952
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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