Dichloromethane → 1-(5-Bromo-4-chloro-2-fluoro-benzenesulfonyl)-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline

HRID 2124597Notes

Reaction equation

HRID 2124597 reaction equation
[Br:1][c:2]1[c:3]([Cl:13])[cH:4][c:5]([F:12])[c:6]([S:8](=[O:9])(=[O:10])[Cl:11])[cH:7]1.[CH3:14][C:15]1([CH3:25])[CH2:16][CH2:17][NH:18][c:19]2[cH:20][cH:21][cH:22][cH:23][c:24]21.[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[Cl:38][CH2:39][Cl:40].[S:33]([Cl:34])([Cl:35])(=[O:36])=[O:37]>>[Br:1][c:2]1[c:3]([Cl:13])[cH:4][c:5]([F:12])[c:6]([S:8](=[O:9])(=[O:10])[N:18]2[CH2:17][CH2:16][C:15]([CH3:14])([CH3:25])[c:24]3[c:19]2[cH:20][cH:21][cH:22][cH:23]3)[cH:7]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 24648Sulfuryl chlorideHCID 132194414,4-Dimethyl-1,2,3,4-tetrahydroquinolineHCID 566047345-Bromo-4-chloro-2-fluoro-benzenesulfonyl chloride

Product 1

HCID 684692731-(5-Bromo-4-chloro-2-fluoro-benzenesulfonyl)-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline

Sources & evidence

ORD record
ord-dcba0b5d68874f55acd33302ac827713
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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