Dimethyl Sulfoxide → 6-(1-methyl-piperidin-4-yloxy)-N-[2-(4-phenoxy-phenyl)-ethyl]-nicotinamide
Reaction equation
[CH3:41][S:42]([CH3:43])=[O:44].[Cl:45][CH2:46][Cl:47].[K+:40].[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[n:8][cH:9][c:10]([C:11](=[O:12])[NH:13][CH2:14][CH2:15][c:16]3[cH:17][cH:18][c:19]([O:22][c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[cH:20][cH:21]3)[cH:29][cH:30]2)[CH2:5][CH2:6]1.[OH-:39].[OH2:48].[OH:31][CH:32]1[CH2:33][CH2:34][N:35]([CH3:38])[CH2:36][CH2:37]1>>[c:7]1([O:31][CH:32]2[CH2:33][CH2:34][N:35]([CH3:38])[CH2:36][CH2:37]2)[n:8][cH:9][c:10]([C:11](=[O:12])[NH:13][CH2:14][CH2:15][c:16]2[cH:17][cH:18][c:19]([O:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[cH:20][cH:21]2)[cH:29][cH:30]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-4f1f598106d649a888e12d3db0cd5377
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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