Dichloromethane → 3-Chloro-6-(1-piperazinyl)pyridazine

HRID 2124954Notes

Reaction equation

HRID 2124954 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][n:16][c:17]([Cl:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:28][CH2:29][Cl:30].[OH:21][C:22]([C:23]([F:24])([F:25])[F:26])=[O:27]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][n:16][c:17]([Cl:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 21925370tert-Butyl 4-(6-chloropyridazin-3-yl)piperazine-1-carboxylate

Product 1

HCID 52949263-Chloro-6-(1-piperazinyl)pyridazine

Sources & evidence

ORD record
ord-89488c7409ee484295ac2e74f557f454
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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