Pyridine → 4-(4-Benzyl-2,5-dimethylpiperazin-1-yl)-2-(trifluoromethyl)benzonitrile
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH:9]([CH3:15])[CH2:10][NH:11][CH:12]([CH3:14])[CH2:13]1.[F:16][c:17]1[cH:18][c:19]([C:25]([F:26])([F:27])[F:28])[c:20]([C:21]#[N:22])[cH:23][cH:24]1.[cH:29]1[cH:30][cH:31][n:32][cH:33][cH:34]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH:9]([CH3:15])[CH2:10][N:11]([c:17]2[cH:18][c:19]([C:25]([F:26])([F:27])[F:28])[c:20]([C:21]#[N:22])[cH:23][cH:24]2)[CH:12]([CH3:14])[CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-8772014c7ef1493799c1a3bd3efcc98f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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