Hydrochloric Acid → N4-Ethyl-N2-(4-(2-methyl-1H-imidazol-1-yl)phenyl)-N4-((tetrahydrofuran-2-yl)methyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diamine

HRID 2125088Notes

Reaction equation

HRID 2125088 reaction equation
[CH2:1]([CH3:2])[N:3]([c:4]1[c:5]2[c:6]([n:7][c:8]([NH:10][c:11]3[cH:12][cH:13][c:14](-[n:17]4[c:18]([CH3:22])[n:19][cH:20][cH:21]4)[cH:15][cH:16]3)[n:9]1)[CH2:23][CH2:24][N:25]([C:27]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH2:26]2)[CH2:34][CH:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:41][OH:42].[ClH:40]>>[CH2:1]([CH3:2])[N:3]([c:4]1[c:5]2[c:6]([n:7][c:8]([NH:10][c:11]3[cH:12][cH:13][c:14](-[n:17]4[c:18]([CH3:22])[n:19][cH:20][cH:21]4)[cH:15][cH:16]3)[n:9]1)[CH2:23][CH2:24][NH:25][CH2:26]2)[CH2:34][CH:35]1[O:36][CH2:37][CH2:38][CH2:39]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 59333772tert-Butyl 4-(ethyl((tetrahydrofuran-2-yl)methyl)amino)-2-(4-(2-methyl-1H-imidazol-1-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

Product 1

HCID 59333811N4-Ethyl-N2-(4-(2-methyl-1H-imidazol-1-yl)phenyl)-N4-((tetrahydrofuran-2-yl)methyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-958d291aed874bdea715f3064c9d87c9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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