Dichloromethane → Ethyl 6-[2-benzyloxy-5-bromobenzylamino]-3-pyridazinecarboxylate

HRID 2125482Notes

Reaction equation

HRID 2125482 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([CH2:11][N:12]([C:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[c:20]2[cH:21][cH:22][c:23]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[n:24][n:25]2)[cH:31][c:32]([Br:35])[cH:33][cH:34]1.[Cl:43][CH2:44][Cl:45].[OH:36][C:37]([C:38]([F:39])([F:40])[F:41])=[O:42]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([CH2:11][NH:12][c:20]2[cH:21][cH:22][c:23]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[n:24][n:25]2)[cH:31][c:32]([Br:35])[cH:33][cH:34]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 22105523Ethyl 6-[N-(2-benzyloxy-5-bromobenzyl)-N-(tert-butoxycarbonyl)amino]-3-pyridazinecarboxylate

Product 1

HCID 22105509Ethyl 6-[2-benzyloxy-5-bromobenzylamino]-3-pyridazinecarboxylate

Sources & evidence

ORD record
ord-8c0efe12c9334dd0ba1521d41dbd960d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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