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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2125628Generated: October 25, 2026

Tetrahydrofuran → Ethyl 2,2-difluoro-3-[4-(5-fluoropyridin-2-yl)phenyl]-3-hydroxybutanoate

https://huagongshe.com/reaction/2125628

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantIodide IonHCID 30165—
ReactantEthyl bromodifluoroacetateHCID 69585—
Reactant1-(4-(5-Fluoropyridin-2-yl)phenyl)ethanoneHCID 59161948—
ReactantHCID 178528036HCID 178528036—
ProductEthyl 2,2-difluoro-3-[4-(5-fluoropyridin-2-yl)phenyl]-3-hydroxybutanoateHCID 68667425—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-397cba4ed73c4c488230f3f1c8660713
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)