1,2-Dichloroethane → Tert-butyl 4-[3-[2-(hydroxymethyl)pyrrolidin-1-yl]propyl]-3-oxopiperazine-1-carboxylate
Reaction equation
[BH3:32].[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[N:14]1[CH2:15][C:16](=[O:24])[N:17]([CH2:20][CH2:21][CH:22]=[CH2:23])[CH2:18][CH2:19]1.[CH3:39][C:40](=[O:41])[OH:42].[CH3:46][C:47]([CH3:48])=[O:49].[CH3:54][CH2:55][OH:56].[Cl:50][CH2:51][CH2:52][Cl:53].[I+3:1]([O-:2])([O-:3])([O-:4])[O-:5].[NH4+:43].[NH:25]1[CH:26]([CH2:27][OH:28])[CH2:29][CH2:30][CH2:31]1.[Na+:6].[OH-:44].[OH2:45].[Os:57](=[O:58])(=[O:59])(=[O:60])=[O:61].[n:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1>>[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[N:14]1[CH2:15][C:16](=[O:24])[N:17]([CH2:20][CH2:21][CH2:22][N:25]2[CH:26]([CH2:27][OH:28])[CH2:29][CH2:30][CH2:31]2)[CH2:18][CH2:19]1Participants
15
Reactant 14
HCID 111,2-Dichloroethane
HCID 176Acetic Acid
HCID 180Acetone
HCID 223Ammonium
HCID 702Ethanol
HCID 923Sodium ion
HCID 961Hydroxide
HCID 962Water
HCID 1049Pyridine
HCID 6331Borane
HCID 30318Osmium Tetroxide
HCID 90908Prolinol
HCID 167232Periodate
HCID 57445033Tert-butyl 4-but-3-enyl-3-oxopiperazine-1-carboxylateProduct 1
Sources & evidence
- ORD record
- ord-cef6fdfc4615469e88bceb3f43fafa4a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…