Dichloromethane → N-(4-methylthiazol-2-yl)-2-(piperazin-1-yl)acetamide

HRID 2126199Notes

Reaction equation

HRID 2126199 reaction equation
[CH3:1][c:2]1[n:3][c:4]([NH:7][C:8]([CH2:9][N:10]2[CH2:11][CH2:12][N:13]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH2:14][CH2:15]2)=[O:23])[s:5][cH:6]1.[Cl:31][CH2:32][Cl:33].[OH:24][C:25]([C:26]([F:27])([F:28])[F:29])=[O:30]>>[CH3:1][c:2]1[n:3][c:4]([NH:7][C:8]([CH2:9][N:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)=[O:23])[s:5][cH:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 57897251tert-Butyl 4-(2-(4-methylthiazol-2-ylamino)-2-oxoethyl)piperazine-1-carboxylate

Product 1

HCID 22164330N-(4-methylthiazol-2-yl)-2-(piperazin-1-yl)acetamide

Sources & evidence

ORD record
ord-4dcf49cf07544c98a1720e4080960d04
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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