Hydrochloric Acid → N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)-3,5-difluorophenyl]-methanesulfonamide

HRID 2126541Notes

Reaction equation

[CH3:1][S:2]([Cl:3])(=[O:4])=[O:5].[ClH:23].[NH2:6][c:7]1[cH:8][c:9]([F:22])[c:10](-[c:14]2[cH:15][cH:16][c:17]([C:20]#[N:21])[n:18]2[CH3:19])[c:11]([F:13])[cH:12]1.[cH:24]1[cH:25][cH:26][n:27][cH:28][cH:29]1>>[CH3:1][S:2](=[O:4])(=[O:5])[NH:6][c:7]1[cH:8][c:9]([F:22])[c:10](-[c:14]2[cH:15][cH:16][c:17]([C:20]#[N:21])[n:18]2[CH3:19])[c:11]([F:13])[cH:12]1

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 1049Pyridine

HCID 31297Methanesulfonyl chloride

HCID 160505305-(4-amino-2,6-difluorophenyl)-1-methyl-1H-pyrrole-2-carbonitrile

Product 1

HCID 16051282N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)-3,5-difluorophenyl]-methanesulfonamide

Sources & evidence

ORD record: ord-7a4cdd77a23b47b8a477ba47c8e53c52
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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