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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2126549Generated: October 29, 2026

Dimethylformamide → 1-Cyclopropyl-6,8-difluoro-7-[4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]-1,3-dihydroisoindol-2-yl]-4-oxoquinoline-3-carboxylic acid

https://huagongshe.com/reaction/2126549

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
Reactant1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acidHCID 535414—
Reactant4-(t-Butyloxycarbonylaminomethyl)isoindolineHCID 19828489—
Product1-Cyclopropyl-6,8-difluoro-7-[4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]-1,3-dihydroisoindol-2-yl]-4-oxoquinoline-3-carboxylic acidHCID 67922418—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-eb36aac8da9645dd9aa0afd4e67ebadc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)