Dimethylformamide → 1-Cyclopropyl-6,8-difluoro-7-[4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]-1,3-dihydroisoindol-2-yl]-4-oxoquinoline-3-carboxylic acid
Reaction equation
[C:21]([CH3:22])([CH3:23])([CH3:24])[O:25][C:26](=[O:27])[NH:28][CH2:29][c:30]1[c:31]2[c:35]([cH:36][cH:37][cH:38]1)[CH2:34][NH:33][CH2:32]2.[CH2:39]1[CH2:40][CH2:41][C:42]2=[N:47][CH2:46][CH2:45][CH2:44][N:43]2[CH2:48][CH2:49]1.[CH:1]1([n:4]2[cH:5][c:6]([C:18](=[O:19])[OH:20])[c:7](=[O:17])[c:8]3[cH:9][c:10]([F:16])[c:11]([F:15])[c:12]([F:14])[c:13]23)[CH2:2][CH2:3]1.[O:50]=[CH:51][N:52]([CH3:53])[CH3:54]>>[CH:1]1([n:4]2[cH:5][c:6]([C:18](=[O:19])[OH:20])[c:7](=[O:17])[c:8]3[cH:9][c:10]([F:16])[c:11]([N:33]4[CH2:32][c:31]5[c:30]([CH2:29][NH:28][C:26]([O:25][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:27])[cH:38][cH:37][cH:36][c:35]5[CH2:34]4)[c:12]([F:14])[c:13]23)[CH2:2][CH2:3]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-eb36aac8da9645dd9aa0afd4e67ebadc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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