Potassium Cation → tert-Butyl 7-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate

HRID 2126645Notes

Reaction equation

HRID 2126645 reaction equation
[C:19](=[O:20])([O-:21])[O-:22].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([OH:18])[cH:13][cH:14][c:15]2[CH2:16][CH2:17]1.[CH3:25][I:26].[CH3:28][N:29]([CH3:30])[CH:31]=[O:32].[K+:23].[K+:24].[OH2:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([O:18][CH3:19])[cH:13][cH:14][c:15]2[CH2:16][CH2:17]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 19660Carbonate IonHCID 10562576Tert-butyl 7-hydroxy-1,2,3,4-tetrahydroisoquinoline-2-carboxylate

Product 1

HCID 54125269tert-Butyl 7-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate

Sources & evidence

ORD record
ord-129d6e6ff39d44d1ba14184fb769a6c1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…