Isobutyl iodide → 1-(6-Amino-5-chloro-2-methoxy-3-pyridinyl)-3-(1-isobutyl-4-piperidinyl)-1-propanone
Reaction equation
[I:21][CH2:22][CH:23]([CH3:24])[CH3:25].[I:45][CH2:46][CH2:47][CH2:48][CH3:49].[NH2:1][c:2]1[c:3]([Cl:20])[cH:4][c:5]([C:10]([CH2:11][CH2:12][CH:13]2[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]2)=[O:19])[c:6]([O:8][CH3:9])[n:7]1.[NH2:26][c:27]1[n:28][c:29]([O:30][CH3:31])[c:32]([C:33](=[O:34])[CH2:35][CH2:36][CH:37]2[CH2:38][CH2:39][NH:40][CH2:41][CH2:42]2)[cH:43][cH:44]1>>[NH2:1][c:2]1[c:3]([Cl:20])[cH:4][c:5]([C:10]([CH2:11][CH2:12][CH:13]2[CH2:14][CH2:15][N:16]([CH2:22][CH:23]([CH3:24])[CH3:25])[CH2:17][CH2:18]2)=[O:19])[c:6]([O:8][CH3:9])[n:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-356aaf0ec0c04110b5ea43f061fd2abd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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