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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2126923Generated: November 1, 2026

Dimethyl Sulfoxide → 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(2-bromophenyl)-6-[4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-3-pyridinyl]-N,2-dimethylpropanamide

https://huagongshe.com/reaction/2126923

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantEthyl AcetateHCID 8857—
Reactant5-(Hydroxymethyl)pyrrolidin-3-olHCID 16767281—
Reactant2-(3,5-bis-trifluoromethyl-phenyl)-N-[4-(2-bromo-phenyl)-6-chloro-pyridin-3-yl]-N-methyl-isobutyramideHCID 60002559—
Product2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(2-bromophenyl)-6-[4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-3-pyridinyl]-N,2-dimethylpropanamideHCID 87304493—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-4a2fc9031cbe4fe1bd249c16307b030a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)