Dimethyl Sulfoxide → 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(2-bromophenyl)-6-[4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-3-pyridinyl]-N,2-dimethylpropanamide
Reaction equation
[CH3:36][S:37](=[O:38])[CH3:39].[CH3:48][CH2:49][O:50][C:51](=[O:52])[CH3:53].[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([C:14](=[O:15])[N:16]([CH3:17])[c:18]2[cH:19][n:20][c:21]([Cl:31])[cH:22][c:23]2-[c:24]2[c:25]([Br:30])[cH:26][cH:27][cH:28][cH:29]2)([CH3:32])[CH3:33])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:34])[F:35].[OH:40][CH2:41][CH:42]1[NH:43][CH2:44][CH:45]([OH:47])[CH2:46]1>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([C:14](=[O:15])[N:16]([CH3:17])[c:18]2[cH:19][n:20][c:21]([N:43]3[CH:42]([CH2:41][OH:40])[CH2:46][CH:45]([OH:47])[CH2:44]3)[cH:22][c:23]2-[c:24]2[c:25]([Br:30])[cH:26][cH:27][cH:28][cH:29]2)([CH3:32])[CH3:33])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:34])[F:35]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-4a2fc9031cbe4fe1bd249c16307b030a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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