Ethanesulfonyl chloride → 5-chloro-N-cyclopentyl-2-[4-[2-(4-ethylsulfonylpiperazin-1-yl)ethyl]-4,5-dihydro-1,3-thiazol-2-yl]-1H-indol-7-amine
Reaction equation
[CH2:30]([CH3:31])[S:32](=[O:33])(=[O:34])[Cl:35].[Cl:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([C:17]3=[N:21][CH:20]([CH2:22][CH2:23][N:24]4[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]4)[CH2:19][S:18]3)[nH:7][c:8]2[c:9]([NH:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:10]1>>[Cl:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([C:17]3=[N:21][CH:20]([CH2:22][CH2:23][N:24]4[CH2:25][CH2:26][N:27]([S:32]([CH2:30][CH3:31])(=[O:33])=[O:34])[CH2:28][CH2:29]4)[CH2:19][S:18]3)[nH:7][c:8]2[c:9]([NH:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-effe2e6e27924c609a52b325ab390d75
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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