Hydrochloric Acid → 3-(aminomethyl)-6-N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-2-N-[1-(4-fluorophenyl)ethyl]pyridine-2,6-diamine

HRID 2127207Notes

Reaction equation

HRID 2127207 reaction equation
[CH3:30][OH:31].[CH:1]1([c:4]2[cH:5][c:6]([NH:9][c:10]3[n:11][c:12]([NH:19][CH:20]([CH3:21])[c:22]4[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]4)[c:13]([C:14]#[N:15])[cH:16][c:17]3[F:18])[n:7][nH:8]2)[CH2:2][CH2:3]1.[ClH:29]>>[CH:1]1([c:4]2[cH:5][c:6]([NH:9][c:10]3[n:11][c:12]([NH:19][CH:20]([CH3:21])[c:22]4[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]4)[c:13]([CH2:14][NH2:15])[cH:16][c:17]3[F:18])[n:7][nH:8]2)[CH2:2][CH2:3]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 67426938HCID 67426938, compound

Product 1

HCID 674549953-(aminomethyl)-6-N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-2-N-[1-(4-fluorophenyl)ethyl]pyridine-2,6-diamine

Sources & evidence

ORD record
ord-c1a0afb459714615ae1c1f988def5866
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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