Water → 3-(2-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]oxy}-1-methylpropoxy)propionic acid tert.-butyl ester

HRID 2127713Notes

Reaction equation

HRID 2127713 reaction equation
[C:30]([CH:31]=[CH2:32])(=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10](-[c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[o:11][c:12]3[n:13][cH:14][n:15][c:16]([O:18][CH:19]([CH:20]([CH3:21])[OH:22])[CH3:23])[c:17]23)[cH:7][cH:8]1.[OH2:39]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10](-[c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[o:11][c:12]3[n:13][cH:14][n:15][c:16]([O:18][CH:19]([CH:20]([CH3:21])[O:22][CH2:32][CH2:31][C:30](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[CH3:23])[c:17]23)[cH:7][cH:8]1

Participants

5

Reactant 4

HCID 962WaterHCID 8028TetrahydrofuranHCID 15458tert-Butyl acrylateHCID 580169433-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]oxy}butan-2-ol

Product 1

HCID 250964163-(2-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]oxy}-1-methylpropoxy)propionic acid tert.-butyl ester

Sources & evidence

ORD record
ord-bf805802127a41ab9bf09474c7defbce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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