Methanol → 6-((trans)-4-aminocyclohexylamino)-8-(cyclopropyl(4-methoxybenzyl)amino)-N-(2-fluoropyridin-4-yl)imidazo[1,2-b]pyridazine-3-carboxamide
Reaction equation
[CH3:42][N:43]1[CH2:44][CH2:45][CH2:46][C:47]1=[O:48].[CH3:49][OH:50].[CH:34]1([NH2:41])[CH2:35][CH2:36][CH:37]([NH2:40])[CH2:38][CH2:39]1.[Cl:1][c:2]1[cH:3][c:4]([N:21]([CH2:22][c:23]2[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]2)[CH:31]2[CH2:32][CH2:33]2)[c:5]2[n:6]([n:7]1)[c:8]([C:11](=[O:12])[NH:13][c:14]1[cH:15][c:16]([F:20])[n:17][cH:18][cH:19]1)[cH:9][n:10]2>>[c:2]1([NH:41][CH:34]2[CH2:35][CH2:36][CH:37]([NH2:40])[CH2:38][CH2:39]2)[cH:3][c:4]([N:21]([CH2:22][c:23]2[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]2)[CH:31]2[CH2:32][CH2:33]2)[c:5]2[n:6]([n:7]1)[c:8]([C:11](=[O:12])[NH:13][c:14]1[cH:15][c:16]([F:20])[n:17][cH:18][cH:19]1)[cH:9][n:10]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-708e51aa06a44bc284b78d1f80c9f947
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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