Dichloromethane → 4-(4-Chlorophenyl)cyclohexan-1-amine

HRID 2128135Notes

Reaction equation

HRID 2128135 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][CH:11]([NH:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[Cl:29][CH2:30][Cl:31].[OH:22][C:23]([C:24]([F:25])([F:26])[F:27])=[O:28]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][CH:11]([NH2:14])[CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67080532[4-(4-Chloro-phenyl)-cyclohexyl]-carbamic acid tert-butyl ester

Product 1

HCID 37154404-(4-Chlorophenyl)cyclohexan-1-amine

Sources & evidence

ORD record
ord-e9c382f473094af5b1583b7b82c1f7a1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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